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Ketogenic Diet And Epilepsy Pdf

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The Ketogenic Diet KD is a modality of treatment used since the s as a treatment for intractable epilepsy. It has been proposed as a dietary treatment that would produce similar benefits to fasting, which is already recorded in the Hippocratic collection. Evidence shows that KD and its variants are a good alternative for non-surgical pharmacoresistant patients with epilepsy of any age, taking into account that the type of diet should be designed individually and that less-restrictive and more-palatable diets are usually better options for adults and adolescents.

History and Origin of the Ketogenic Diet

Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: The Ketogenic Diet KD is a modality of treatment used since the s as a treatment for intractable epilepsy. It has been proposed as a dietary treatment that would produce similar benefits to fasting, which is already recorded in the Hippocratic collection.

Ketogenic Diet and Epilepsy: What We Know So Far

Citation Information : Journal of Epileptology. Finding an effective epilepsy treatment has been a challenge in medicine for centuries. This gives an incentive to search for therapies other than pharmacotherapy, e. The present review paper aims to present the current state of knowledge regarding the effectiveness of the KD, its mechanism of action, indications, method of treatment and potential adverse effects. The review covers relevant most recent up to March papers using PubMed and Medline databases.

With the rising demand for ketogenic diet therapy in adult epilepsy, there is a need for research describing the real-life effectiveness, retention, and safety of relevant services. Of the first referrals, 42 31 females, 11 males; mean age The most common reasons for discontinuing MKD were side effects and diet restrictiveness. The most common side effects were weight loss, gastrointestinal symptoms and low mood. This study demonstrates that MKD can be effective in adults, although, even with regular dietetic support, retention rates remain low, and periods of worsening seizure frequency are common. Approximately one third of adult epilepsy patients do not achieve seizure freedom with antiepileptic drugs AEDs [ 1 , 2 ].

Ketogenic diets for drug-resistant epilepsy

Jump to navigation. Epilepsy is a disorder where recurrent seizures are caused by abnormal electrical discharges from the brain. In most people, seizures can be controlled by one or more antiepileptic medicines.

Ketogenic Diet and Epilepsy: What We Know So Far

Ketogenic Diet and Epilepsy: What We Know So Far

Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled. Received 27 August Published 25 November Volume Pages — Review by Single anonymous peer review.

The Ketogenic Diet KD is a modality of treatment used since the s as a treatment for intractable epilepsy. It has been proposed as a dietary treatment that would produce similar benefits to fasting, which is already recorded in the Hippocratic collection. Evidence shows that KD and its variants are a good alternative for non-surgical pharmacoresistant patients with epilepsy of any age, taking into account that the type of diet should be designed individually and that less-restrictive and more-palatable diets are usually better options for adults and adolescents. Epilepsy is a disabling and common neurological disease, which can be controlled successfully in most patients with one or more antiepileptic drugs. Some of these patients are not surgery candidates, so it is necessary to search for alternative treatments for epilepsy such as palliative surgery, neuromodulation, and a ketogenic diet KD. The classic ketogenic diet CKD consists of a high-fat and low-protein and carbohydrate diet, with restricted calories and fluids.


The ketogenic diet (KD) was found to be effective in treatment of intractable seizures. The KD consists of a high fat, low carbohydrate and.


Ketogenic diets for drug-resistant epilepsy

From the Section on Pediatrics, Mayo Clinic. During the last two and one-half years, the ketogenic, or high fat, diet has been given a trial in the treatment of epilepsy in childhood. Thirty-seven patients with essential or idiopathic epilepsy, whose parents were able to comprehend and carry out the diet intelligently at home, have been observed over periods of from four months to two and one-half years.

Metrics details. The incidence of epilepsy is greatest in the first 2 years of life, an age group where there is generally a poor prognosis for both seizure control and neurodevelopmental outcome. Early control of seizures can be associated with better developmental outcome but many of the epilepsies presenting in infancy are poorly responsive to antiepileptic medication. The ketogenic diet KD is a high-fat, low-carbohydrate diet designed to mimic the effects of starvation on the body. Dietary fat is converted into ketones in the body and used as an energy source by the brain.

Epilepsy and the Ketogenic Diet pp Cite as. However, fasting as a treatment for seizures was less recognized. Fasting is the only therapeutic measure against epilepsy recorded in the Hippocratic collection 1. In the fifth century BC, Hippocrates reported on a man who had been seized by epileptic convulsions after having anointed himself before the fire in a bath, in winter.

Так, чтобы не осталось и следа. Сьюзан нахмурилась.

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Amber L. 13.05.2021 at 10:59

PDF | The ketogenic diet (KD), a high-fat, low-carbohydrate, and adequate-​protein diet is an established, effective nonpharmacologic treatment option | Find.

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